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Article

The ACTN3 R577X polymorphism in East and West African athletes.

Medicine and science in sports and exercise - 1 Nov 2007

Yang Nan, MacArthur Daniel G, Wolde Bezabhe, Onywera Vincent O, Boit Michael K, Lau Sau Yin Mary-Ann, Wilson Richard H, Scott Robert A, Pitsiladis Yannis P, North Kathryn

Abstract excerpt

PURPOSE: To determine the frequency of the ACTN3 R577X polymorphism (functional R allele and nonfunctional X allele) in a variety of African populations and to examine its influence on the success of elite East African endurance runners and West African sprinters. METHODS: The R577X polymorphism was genotyped in 198 Ethiopian controls and 76 elite Ethiopian endurance athletes, 158 Kenyan controls and 284 elite...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17986906
DOI: 10.1249/mss.0b013e31814844c9

Genes

ACTN3

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

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Is evolutionary loss our gain? The role of ACTN3 p.Arg577Ter (R577X) genotype in athletic performance, ageing, and diseaseSemantic proximity Read ↗

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