Article
The origin and evolution of enamel mineralization genes.
Cells, tissues, organs - 1 Jan 2007
Sire Jean-Yves, Davit-Béal Tiphaine, Delgado Sidney, Gu Xun
Abstract excerpt
BACKGROUND/AIMS: Enamel and enameloid were identified in early jawless vertebrates, about 500 million years ago (MYA). This suggests that enamel matrix proteins (EMPs) have at least the same age. We review the current data on the origin, evolution and relationships of enamel mineralization genes. METHODS AND RESULTS: Three EMPs are secreted by ameloblasts during enamel formation: amelogenin (AMEL), ameloblastin...
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