The origin and evolution of enamel mineralization genes.

doi:10.1159/000102679

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Article

The origin and evolution of enamel mineralization genes.

Cells, tissues, organs - 1 Jan 2007

Sire Jean-Yves, Davit-Béal Tiphaine, Delgado Sidney, Gu Xun

Abstract excerpt

BACKGROUND/AIMS: Enamel and enameloid were identified in early jawless vertebrates, about 500 million years ago (MYA). This suggests that enamel matrix proteins (EMPs) have at least the same age. We review the current data on the origin, evolution and relationships of enamel mineralization genes. METHODS AND RESULTS: Three EMPs are secreted by ameloblasts during enamel formation: amelogenin (AMEL), ameloblastin...

Topics

Amelogenin
Amino Acid Sequence
Animals
Chromosome Mapping
Dental Enamel
Dental Enamel Proteins
Evolution, Molecular
Gene Duplication
Humans
Molecular Sequence Data
Mutation
Phylogeny
Sequence Analysis, Protein
Tooth Calcification

Source

Open in PubMed

Identifiers

PMID: 17627117
DOI: 10.1159/000102679

Genes

AMBN
AMTN
ENAM
ODAM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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