E<scp>namelin and</scp> A<scp>utosomal-dominant</scp> A<scp>melogenesis</scp> I<scp>mperfecta</scp>

Abstract excerpt

Dental enamel forms as a progressively thickening extracellular layer by the action of proteins secreted by ameloblasts. The most abundant enamel protein is amelogenin, which is expressed primarily from a gene on the X-chromosome (AMELX). The two most abundant non-amelogenin enamel proteins are ameloblastin and enamelin, which are expressed from the AMBN and ENAM genes, respectively. The human AMBN and ENAM genes...

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