Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Evolutionary Analysis Suggests That AMTN is Enamel-specific and a Candidate for AI

11 Sept 2012

Abstract excerpt

Molecular evolutionary analysis is an efficient method to predict and/or validate amino acid substitutions that could lead to a genetic disease and to highlight residues and motifs that could play an important role in the protein structure and/or function. We have applied such analysis to amelotin (AMTN), a recently identified enamel protein in the rat, mouse, and humans. An in silico search for AMTN provided 42...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bone and Dental Protein Studies
Share to dental development and anomalies
Share to Oral microbiology and periodontitis research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22968158
DOI: 10.1177/0022034512460551

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Evolutionary Analysis Suggests That AMTN is Enamel-specific and a Candidate for AIPMID 22968158Read ↗

The origin and evolution of enamel mineralization genes.Semantic proximity Read ↗

Evolutionary analysis of selective constraints identifies ameloblastin (AMBN) as a potential candidate for amelogenesis imperfecta.Semantic proximity Read ↗

Evolutionary analysis of mammalian enamelin, the largest enamel protein, supports a crucial role for the 32-kDa peptide and reveals selective adaptation in rodents and primates.Semantic proximity Read ↗

E<scp>namelin and</scp> A<scp>utosomal-dominant</scp> A<scp>melogenesis</scp> I<scp>mperfecta</scp>Semantic proximity Read ↗

Molecular evolution of amelogenin in mammals.Semantic proximity Read ↗

Deletion of amelotin exons 3-6 is associated with amelogenesis imperfecta.Semantic proximity Read ↗

Alteration of conserved alternative splicing in AMELX causes enamel defects.Semantic proximity Read ↗

Evolutionary analysis of FAM83H in vertebrates.Semantic proximity Read ↗

Molecular Evolution of Tooth-Related Genes Provides New Insights into Dietary Adaptations of Mammals.Semantic proximity Read ↗

Simple recessive mutation in ENAM is associated with amelogenesis imperfecta in Italian Greyhounds.Semantic proximity Read ↗

A novel AMELX mutation causes hypoplastic amelogenesis imperfecta.Semantic proximity Read ↗

Molecular Evolution of the Tissue-nonspecific Alkaline Phosphatase Allows Prediction and Validation of Missense Mutations Responsible for HypophosphatasiaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.