Article
The lethal phenotype of cancer: the molecular basis of death due to malignancy.
CA: a cancer journal for clinicians - 1 Jan 2000
Loberg Robert D, Bradley Deborah A, Tomlins Scott A, Chinnaiyan Arul M, Pienta Kenneth J
Abstract excerpt
The last decade has seen an explosion in knowledge of the molecular basis and treatment of cancer. The molecular events that define the lethal phenotype of various cancers--the genetic and cellular alterations that lead to a cancer with a poor or incurable prognosis--are being defined. While these studies describe the cellular events of the lethal phenotype of cancer in detail, how these events result in the...
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