Article
The molecular biology of cancer.
Molecular aspects of medicine - 1 Dec 2000
Bertram J S
Abstract excerpt
The process by which normal cells become progressively transformed to malignancy is now known to require the sequential acquisition of mutations which arise as a consequence of damage to the genome. This damage can be the result of endogenous processes such as errors in replication of DNA, the intrinsic chemical instability of certain DNA bases or from attack by free radicals generated during metabolism. DNA...
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