The molecular basis of cancer and the development of targeted therapy.

doi:10.1016/j.suc.2008.09.016

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Article

The molecular basis of cancer and the development of targeted therapy.

The Surgical clinics of North America - 1 Feb 2009

Riley Lee B, Desai Darius C

Abstract excerpt

The sequencing of the human genome and the ability to rapidly identify genes and proteins, both normal and mutant, that are involved in tumorigenesis and malignant phenotypes, have changed the ability to understand malignant cells. Understanding and applying this information to the diagnosis and treatment of cancer are facilitated best with a multidisciplinary team. The cancer surgeon plays a pivotal role in this...

Topics

Antineoplastic Agents
Breast Neoplasms
DNA Repair
Disease Progression
Epigenesis, Genetic
Humans
Neoplasms
Neoplastic Stem Cells
Pancreatic Neoplasms
Phenotype
Vascular Endothelial Growth Factor A

Source

Open in PubMed

Identifiers

PMID: 19186227
DOI: 10.1016/j.suc.2008.09.016

Provenance

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