Article
The association between RAD18 Arg302Gln polymorphism and the risk of human non-small-cell lung cancer.
Journal of cancer research and clinical oncology - 1 Feb 2008
Kanzaki Hirotaka, Ouchida Mamoru, Hanafusa Hiroko, Yamamoto Hiromasa, Suzuki Hiromitsu, Yano Masaaki, Aoe Motoi, Imai Kazue, Date Hiroshi, Nakachi Kei, Shimizu Kenji
Abstract excerpt
PURPOSE: The repair enzyme RAD18 plays a key role in the post-replication repair process in various organisms from yeast to human, and the molecular function of the RAD18 protein has been elucidated. Single nucleotide polymorphism (SNP) of arginine (Arg, CGA) or glutamine (Gln, CAA) at codon 302...
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