Article
RAD18 polymorphisms are associated with platinum-based chemotherapy toxicity in Chinese patients with non-small cell lung cancer.
Acta pharmacologica Sinica - 1 Nov 2016
Chu Tian-Qing, Li Rong, Shao Min-Hua, Ye Jun-Yi, Han Bao-Hui
Abstract excerpt
AIM: Although targeted therapy is very efficient for lung cancer, traditional platinum-based chemotherapies are still the principal strategy in the absence of positive biomarkers. The aim of the present study is to evaluate the contribution of RAD18 polymorphisms to platinum-chemotherapy response and its potential side effects in Chinese patients with non-small cell lung cancer (NSCLC). METHODS: A total of 1021...
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