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Article

Association of CYP3A4*18B polymorphisms with the pharmacokinetics of cyclosporine in healthy subjects.

Xenobiotica; the fate of foreign compounds in biological systems - 1 Mar 2007

Hu Y F, Tu J H, Tan Z R, Liu Z Q, Zhou G, He J, Wang D, Zhou H H

Abstract excerpt

The aim of this study is to evaluate the association of the CYP3A4*18B genotype with the cyclosporine metabolism in healthy subjects. We employed PCR-RFLP assays for analysis of the CYP3A4*18B genotype. Each of 26 subjects, comprising 12 CYP3A4*1/*1, 12 CYP3A4*1/*18B and 2 CYP3A4*18B/*18B, was gi...

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Source

Identifiers

PMID: 17624028
DOI: 10.1080/00498250601149206

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17624028-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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