Article
RAVE is essential for the efficient assembly of the C subunit with the vacuolar H(+)-ATPase.
The Journal of biological chemistry - 7 Sept 2007
Smardon Anne M, Kane Patricia M
Abstract excerpt
The RAVE complex is required for stable assembly of the yeast vacuolar proton-translocating ATPase (V-ATPase) during both biosynthesis of the enzyme and regulated reassembly of disassembled V(1) and V(0) sectors. It is not yet known how RAVE effects V-ATPase assembly. Previous work has shown that V(1) peripheral or stator stalk subunits E and G are critical for binding of RAVE to cytosolic V(1) complexes,...
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