Article

Interaction of yeast V-ATPase with TLDc protein Rtc5p

2025-05-24

Abstract excerpt

The eukaryotic vacuolar H + -ATPase (V-ATPase) is regulated by reversible disassembly into autoinhibited V 1 -ATPase and V o proton channel subcomplexes, a mode of regulation conserved from yeast to humans. While signals that govern V-ATPase assembly have been studied in the cellular context, the molecular mechanisms of the process at the level of the enzyme remain poorly understood. We recently discovered that...

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Literature Corpus work: a14d2aa1-5532-5651-83ed-c4365784b548
DOI: 10.1101/2025.05.24.655954

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