Article
Expression of L* protein of Theiler's murine encephalomyelitis virus in the chronic phase of infection.
The Journal of general virology - 1 Aug 2007
Asakura Kunihiko, Murayama Harunobu, Himeda Toshiki, Ohara Yoshiro
Abstract excerpt
The DA strain and other members of the TO subgroup of Theiler's murine encephalomyelitis virus synthesize the L* protein from an alternative initiation codon. L* is considered to play a key role in viral persistence and demyelination in susceptible strains of mice, although this hypothesis is still controversial. By using a mutant virus that expresses FLAG epitope-tagged L*, it was demonstrated previously that L*...
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