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Article

Clonal expansion of CD8+ effector T cells in childhood tuberculosis.

Journal of immunology (Baltimore, Md. : 1950) - 15 Jul 2007

Jacobsen Marc, Detjen Anne K, Mueller Henrik, Gutschmidt Andrea, Leitner Sandra, Wahn Ulrich, Magdorf Klaus, Kaufmann Stefan H E

Abstract excerpt

The role of CD8(+) T cells in human tuberculosis (TB) remains elusive. We analyzed the T cell repertoire and phenotype in 1) children with active TB (< or =4 years), 2) healthy latently Mycobacterium tuberculosis-infected children, and 3) noninfected age-matched (tuberculin skin test-negative) controls. Ex vivo phenotyping of T cell subpopulations by flow cytometry revealed a significant increase in the...

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Share to CD8-Positive T-Lymphocytes
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17617626
DOI: 10.4049/jimmunol.179.2.1331

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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