Article
Alpha-synuclein: its biological function and role in neurodegenerative diseases.
Journal of molecular neuroscience : MN - 1 Apr 2003
Kaplan Batia, Ratner Vladimir, Haas Elisha
Abstract excerpt
Alpha-synuclein is regarded as a presynaptic protein, which may play an important role in neuronal plasticity. However, the actual physiological function of this protein is not completely clear. Abnormal accumulation of fibrillar alpha-synuclein in Lewy bodies, as well as mutations in the alpha-synuclein gene identified in the familial forms of Parkinson's disease, point to a central role of this protein in the...
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