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Article

Role of the linker between the N- and C-terminal domains in the stability and folding of rabbit muscle creatine kinase.

The international journal of biochemistry & cell biology - 1 Jan 2007

He Hua-Wei, Feng Shan, Pang Min, Zhou Hai-Meng, Yan Yong-Bin

Abstract excerpt

Domain-domain interactions may be very important to the structure and functions of many multidomain proteins. However, little is known about the role of the linker in the folding, stability and function of multidomain proteins. In this research, muscle creatine kinase (CK), a dimeric two-domain protein, was used as a model protein to investigate the role of the linker in CK activity, stability and folding by...

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Identifiers

PMID: 17616428
DOI: 10.1016/j.biocel.2007.04.028

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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