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Article

The associated contributions of p53 and the DNA mismatch repair protein Msh6 to spontaneous tumorigenesis.

Carcinogenesis - 1 Oct 2007

Young Leah C, Keuling Angela M, Lai Raymond, Nation Patrick N, Tron Victor A, Andrew Susan E

Abstract excerpt

DNA mismatch repair (MMR) is a highly conserved system that repairs DNA adducts acquired during replication, as well as some forms of exogenous/endogenous DNA damage. Additionally, MMR proteins bind to DNA adducts that are not removed by MMR and influence damage-response mechanisms other than repair. Hereditary non-polyposis colorectal cancer, as well as mouse models for MMR deficiency, illustrate that MMR...

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Identifiers

PMID: 17615258
DOI: 10.1093/carcin/bgm153

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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