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Article

An integrative pan-cancer analysis reveals the oncogenic role of mutS homolog 6 (MSH6) in human tumors.

Aging - 7 Dec 2021

Zhan Haibo, Mo Fengbo, Xu Qiang, Wang Song, Zhang Bin, Liu Xuqiang, Dai Min, Liu Hucheng

Abstract excerpt

There are three most important mismatch repair genes in the mismatch repair system, MSH6 is one of them and it plays an essential role in DNA mismatch repair. Several emerging cell- or animal-based studies have verified that MSH6 mutations are closely linked to the occurrence, progression or metastasis of cancer, but there is still no practicable pan-cancer analysis. On account of the available datasets of the...

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Identifiers

PMID: 34941572
DOI: 10.18632/aging.203745
PMCID: PMC8714153

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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