Article
Complex insertion/deletion polymorphism in NOD1 (CARD4) is not associated with inflammatory bowel disease susceptibility in East Anglia panel.
Inflammatory bowel diseases - 1 Oct 2006
Tremelling Mark, Hancock Laura, Bredin Francesca, Sharpstone Daniel, Bingham Shiela A, Parkes Miles
Abstract excerpt
BACKGROUND AND AIMS: Genetic association between inflammatory bowel disease (IBD) and NOD1 (CARD4) has recently been reported. This gene has structural similarity to NOD2 (CARD15), a confirmed susceptibility gene for Crohn"s disease (CD). The NOD1 association was strongest at novel complex indel ND1 + 32656. Our aim was to ascertain the contribution of ND1 + 32656 variants to IBD in a large independent United...
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