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Article

Haplotype structure and association to Crohn's disease of CARD15 mutations in two ethnically divergent populations.

European journal of human genetics : EJHG - 1 Jan 2003

Croucher Peter J P, Mascheretti Silvia, Hampe Jochen, Huse Klaus, Frenzel Henning, Stoll Monika, Lu Tim, Nikolaus Susanna, Yang Suk-Kyun, Krawczak Michael, Kim Won Ho, Schreiber Stefan

Abstract excerpt

Current debate focuses on the relevance of linkage disequilibrium (LD), ethnicity and underlying haplotype structure to the search for genes involved in complex disorders. The recently described association between single nucleotide polymorphisms (SNPs) of the CARD15 (NOD2) gene and Crohn's disease (CD) in populations of north-European descent provides a test case that we have subjected to detailed SNP haplotype...

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Identifiers

PMID: 12529700
DOI: 10.1038/sj.ejhg.5200897

Genes

NOD2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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