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Article

The regulatory domains of CNA have different effects on the inhibition of CN activity by FK506 and CsA.

IUBMB life - 1 Jun 2007

Wang Hai-Long, Du Yan-Wei, Xiang Ben-Qiong, Lin Wei-Lin, Wei Qun

Abstract excerpt

Calcineurin (CN) is the common receptor for two immunophilin-immunosuppressant complexes, Cyp-CsA and FKBP-FK506. Calcineurin is composed of a catalytic subunit (CNA) and a regulatory subunit (CNB). CNA contains the catalytic domain and three regulatory domains: a CNB-binding domain (BBH, 350-370), a calmodulin- binding domain (CBD, 389-413), and an autoinhibitory domain (AID, 457-482). To investigate the effects...

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PMID: 17613169
DOI: 10.1080/15216540701370721

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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