Article
Mutation in HSF4 associated with early but not late-onset hereditary cataract in the Boston Terrier.
The Journal of heredity - 1 Jan 2007
Mellersh Cathryn S, Graves Kathryn T, McLaughlin Bryan, Ennis Rosalyn B, Pettitt Louise, Vaudin Mark, Barnett Keith C
Abstract excerpt
Primary hereditary cataract (HC) is one of the most common disorders in purebred dogs and is a leading cause of blindness. Boston Terriers suffer from 2 distinct forms of HC which occur at different ages and which are different in their appearance and progression. Early-onset hereditary cataract (EHC) affects dogs within the first few months of life, is always progressive and bilateral, and results in total...
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