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Article

Dogs and humans share a common susceptibility gene SRBD1 for glaucoma risk.

PloS one - 1 Jan 2013

Kanemaki Nobuyuki, Tchedre Kissaou T, Imayasu Masaki, Kawarai Shinpei, Sakaguchi Masahiro, Yoshino Atsushi, Itoh Norihiko, Meguro Akira, Mizuki Nobuhisa

Abstract excerpt

Glaucoma is a degenerative optic neuropathy that is associated with elevated intraocular pressure. Primary open angle glaucoma is the most common type of glaucoma in canines, and its highest incidence among dog breeds has been reported in Shiba-Inus, followed by Shih-Tzus. These breeds are known to have an abnormal iridocorneal angle and dysplastic prectinate ligament. However, the hereditary and genetic...

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Source

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Identifiers

PMID: 24040232
DOI: 10.1371/journal.pone.0074372
PMCID: PMC3770690

Genes

SRBD1
ADAMTS10
ELOVL5

Provenance

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