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Article

Involvement of hyaluronan in regulation of fibroblast phenotype.

The Journal of biological chemistry - 31 Aug 2007

Meran Soma, Thomas David, Stephens Philip, Martin John, Bowen Timothy, Phillips Aled, Steadman Robert

Abstract excerpt

This study aimed to understand the role of the matrix polysaccharide, hyaluronan (HA), in influencing the scarring process by assessing its impact on regulating fibroblast behavior. Donor-matched human oral and dermal fibroblasts were used as models of nonscarring and scarring fibroblast phenotypes, respectively. Phenotypic differences in these two fibroblast populations were assessed and related to differences...

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Source

Identifiers

PMID: 17611197
DOI: 10.1074/jbc.M700773200

Genes

HAS1
HAS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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