Is fibroblast heterogeneity relevant to the health, diseases, and treatments of periodontal tissues?

doi:10.1177/10454411970080030201

Article

Is fibroblast heterogeneity relevant to the health, diseases, and treatments of periodontal tissues?

Critical reviews in oral biology and medicine : an official publication of the American Association of Oral Biologists - 1 Jan 1997

Lekic P C, Pender N, McCulloch C A

Abstract excerpt

There are wide variations of gene expression and strikingly different responses to extracellular signals among different fibroblast populations. This has prompted a large number of in vitro studies which suggest that fibroblasts are not homogeneous but instead comprise multiple subpopulations wit...

Topics

Apoptosis
Biomarkers
Cell Differentiation
Fibroblasts
Gingiva
Humans
Periodontal Diseases
Periodontal Ligament
Phenotype
Stromal Cells
Wound Healing

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.