Article
Is fibroblast heterogeneity relevant to the health, diseases, and treatments of periodontal tissues?
Critical reviews in oral biology and medicine : an official publication of the American Association of Oral Biologists - 1 Jan 1997
Lekic P C, Pender N, McCulloch C A
Abstract excerpt
There are wide variations of gene expression and strikingly different responses to extracellular signals among different fibroblast populations. This has prompted a large number of in vitro studies which suggest that fibroblasts are not homogeneous but instead comprise multiple subpopulations with extensive site-to-site and intra-site variations. Conceivably, either fibroblasts are not all created equal, or,...
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