Article
Replication and identification of novel variants at TCF7L2 associated with type 2 diabetes in Hong Kong Chinese.
The Journal of clinical endocrinology and metabolism - 1 Sept 2007
Ng Maggie C Y, Tam Claudia H T, Lam Vincent K L, So Wing-Yee, Ma Ronald C W, Chan Juliana C N
Abstract excerpt
OBJECTIVE: Variations at a large linkage disequilibrium (LD) block of transcription factor 7-like 2 gene (TCF7L2) were reported to be associated with type 2 diabetes (T2D) in Icelandic, Danish and European-American populations and further replicated in other populations of European, African, and Asian ancestries. However, data for Chinese and comprehensive survey of the whole gene are lacking. DESIGN: We...
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