Article
Genetic variants of TCF7L2 are associated with type 2 diabetes in a northeastern Chinese population.
Gene - 10 Mar 2012
Qiao Hong, Zhang Xuelong, Zhao Xuedan, Zhao Yanling, Xu Lidan, Sun Haiming, Fu Songbin
Abstract excerpt
Variants in the gene encoding transcription factor 7-like 2 (TCF7L2) are associated with type 2 diabetes mellitus (T2D) in several ethnic groups. Two intronic variants, rs290487 and rs11196218, were originally identified as T2D modifiers in Hong Kong Chinese and Taiwan Chinese populations, respectively. However, discrepancies were noted in subsequent replicated studies. In this study, an association of these two...
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