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Article

The spread of alphabetical writing may have favored the latest variant of the ASPM gene.

Medical hypotheses - 1 Jan 2008

Frost Peter

Abstract excerpt

ASPM, a gene that regulates brain growth, has evolved considerably in the primate lineage that leads to humans. It continued to evolve even after the emergence of modern humans, with the latest ASPM variant arising about 6000 years ago somewhere in the Middle East. The new variant then proliferated within and outside this region, reaching higher incidences in the Middle East (37-52%) and in Europe (38-50%) than...

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Source

Identifiers

PMID: 17604569
DOI: 10.1016/j.mehy.2007.04.039

Genes

ASPM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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