Article
Neurite outgrowth on a fibronectin isoform expressed during peripheral nerve regeneration is mediated by the interaction of paxillin with alpha4beta1 integrins.
BMC neuroscience - 29 Jun 2007
Vogelezang Mariette, Forster Ulrike B, Han Jaewon, Ginsberg Mark H, ffrench-Constant Charles
Abstract excerpt
BACKGROUND: The regeneration of peripheral nerve is associated with a change in the alternative splicing of the fibronectin primary gene transcript to re-express embryonic isoforms containing a binding site for alpha4beta1 integrins that promote neurite outgrowth. Here we use PC12 cells to examin...
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