Article
A genetic mosaic analysis with a repressible cell marker screen to identify genes involved in tracheal cell migration during Drosophila air sac morphogenesis.
Genetics - 1 Aug 2007
Chanut-Delalande Hélène, Jung Alain C, Lin Li, Baer Magdalena M, Bilstein Andreas, Cabernard Clemens, Leptin Maria, Affolter Markus
Abstract excerpt
Branching morphogenesis of the Drosophila tracheal system relies on the fibroblast growth factor receptor (FGFR) signaling pathway. The Drosophila FGF ligand Branchless (Bnl) and the FGFR Breathless (Btl/FGFR) are required for cell migration during the establishment of the interconnected network of tracheal tubes. However, due to an important maternal contribution of members of the FGFR pathway in the oocyte, a...
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