Article
A molecular link between FGF and Dpp signaling in branch-specific migration of the Drosophila trachea.
Developmental biology - 1 May 2005
Myat Monn Monn, Lightfoot Harrell, Wang Ping, Andrew Deborah J
Abstract excerpt
The tracheal system of Drosophila embryos achieves its archetypal branching pattern through a series of cell migration events requiring the FGF, Dpp, and Wg/WNT signaling pathways. To gain insight into tracheal cell migration, we performed an F4 EMS mutagenesis screen to generate and characterize new mutations resulting in tracheal defects. From 2591 mutagenized third chromosome lines, we identified 33 mutations...
Topics
- Animals
- Body Patterning
- Cell Movement
- DNA-Binding Proteins
- Drosophila Proteins
- Drosophila melanogaster
- Fibroblast Growth Factors
- Gene Expression Regulation, Developmental
- In Situ Hybridization
- Morphogenesis
- Mutagenesis
- Mutation
- Nerve Tissue Proteins