Article
Human glycine alpha1 receptor inhibition by quercetin is abolished or inversed by alpha267 mutations in transmembrane domain 2.
Brain research - 3 Aug 2007
Lee Byung-Hwan, Lee Jun-Ho, Yoon In-Soo, Lee Joon-Hee, Choi Sun-Hye, Pyo Mi Kyung, Jeong Sang Min, Choi Woo-Sung, Shin Tae-Joon, Lee Sang-Mok, Rhim Hyewhon, Park Yong-Sun, Han Ye Sun, Paik Hyun-Dong, Cho Ssang-Goo, Kim Cheon-Ho, Lim Yoong-Ho, Nah Seung-Yeol
Abstract excerpt
Quercetin, one of the flavonoids, is a compound of low molecular weight found in fruits and vegetables. Besides its antioxidative effect, quercetin also shows a wide range of diverse neuropharmacological actions. However, the cellular mechanisms of quercetin's actions, especially on ligand-gated ion channels and synaptic transmissions, are not well studied. We investigated the effect of quercetin on the human...
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