Article
In vivo sequence variation of the human immunodeficiency virus type 1 env gene: evidence for recombination among variants found in a single individual.
AIDS research and human retroviruses - 1 Nov 1991
Howell R M, Fitzgibbon J E, Noe M, Ren Z J, Gocke D J, Schwartzer T A, Dubin D T
Abstract excerpt
To assess in vivo sequence heterogeneity of the human immunodeficiency virus type 1 (HIV-1) env gene, we used the polymerase chain reaction to amplify proviral sequences present in peripheral blood mononuclear cell DNA of a patient with acquired immunodeficiency syndrome (AIDS). The amplified env gene fragment (575 bp) contains the first hypervariable region and part of the first conserved region. Eleven and...
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