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Article

Regulation of HTLV-1 Gag budding by Vps4A, Vps4B, and AIP1/Alix.

Virology journal - 2 Jul 2007

Urata Shuzo, Yokosawa Hideyoshi, Yasuda Jiro

Abstract excerpt

BACKGROUND: HTLV-1 Gag protein is a matrix protein that contains the PTAP and PPPY sequences as L-domain motifs and which can be released from mammalian cells in the form of virus-like particles (VLPs). The cellular factors Tsg101 and Nedd4.1 interact with PTAP and PPPY, respectively, within the HTLV-1 Gag polyprotein. Tsg101 forms a complex with Vps28 and Vps37 (ESCRT-I complex) and plays an important role in...

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Share to ATPases Associated with Diverse Cellular Activities
Share to Endosomal Sorting Complexes Required for Transport

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to gag Gene Products, Human Immunodeficiency Virus

Share to Gene Products, gag

Share to Human T-lymphotropic virus 1

Share to Retroviridae Proteins, Oncogenic

Share to Vacuolar Proton-Translocating ATPases

Share to Vesicular Transport Proteins

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Identifiers

PMID: 17601348
DOI: 10.1186/1743-422X-4-66
PMCID: PMC1920503

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Regulation of HTLV-1 Gag budding by Vps4A, Vps4B, and AIP1/Alix.PMID 17601348Read ↗

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