Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Nedd4 Regulates Egress of Ebola Virus-Like Particles from Host Cells

26 Aug 2003

Abstract excerpt

Ebola virus budding is mediated by two proline-rich motifs, PPxY and PTAP, within the viral matrix protein VP40. We have previously shown that a Nedd4-like protein BUL1, but not Nedd4, positively regulates budding of type D retrovirus Mason-Pfizer monkey virus (J. Yasuda, E. Hunter, M. Nakao, and H. Shida, EMBO Rep. 3:636-640, 2002). Here, we report that the cellular E3 ubiquitin ligase Nedd4 regulates budding of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to HIV Research and Treatment
Share to Mosquito-borne diseases and control
Share to Viral Infections and Outbreaks Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 12941909
DOI: 10.1128/jvi.77.18.9987-9992.2003

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Nedd4 Regulates Egress of Ebola Virus-Like Particles from Host CellsPMID 12941909Read ↗

Overlapping Motifs (PTAP and PPEY) within the Ebola Virus VP40 Protein Function Independently as Late Budding Domains: Involvement of Host Proteins TSG101 and VPS-4Semantic proximity Read ↗

Functional involvement of a novel Nedd4-like ubiquitin ligase on retrovirus budding.Semantic proximity Read ↗

Budding of PPxY-Containing Rhabdoviruses Is Not Dependent on Host Proteins TGS101 and VPS4ASemantic proximity Read ↗

ISG15 inhibits Ebola VP40 VLP budding in an L-domain-dependent manner by blocking Nedd4 ligase activity.Semantic proximity Read ↗

Ubiquitin Ligase WWP1 Interacts with Ebola Virus VP40 To Regulate EgressSemantic proximity Read ↗

ITCH E3 Ubiquitin Ligase Interacts with Ebola Virus VP40 To Regulate BuddingSemantic proximity Read ↗

ALIX Rescues Budding of a Double PTAP/PPEY L-Domain Deletion Mutant of Ebola VP40: A Role for ALIX in Ebola Virus EgressSemantic proximity Read ↗

Nedd4.1-mediated ubiquitination and subsequent recruitment of Tsg101 ensure HTLV-1 Gag trafficking towards the multivesicular body pathway prior to virus budding.Semantic proximity Read ↗

Regulation of Marburg virus (MARV) budding by Nedd4.1: a different WW domain of Nedd4.1 is critical for binding to MARV and Ebola virus VP40Semantic proximity Read ↗

Regulation of HTLV-1 Gag budding by Vps4A, Vps4B, and AIP1/Alix.Semantic proximity Read ↗

Role of Nedd4 and ubiquitination of Rous sarcoma virus Gag in budding of virus-like particles from cells.Semantic proximity Read ↗

Chaperone-Mediated Autophagy Protein BAG3 Negatively Regulates Ebola and Marburg VP40-Mediated EgressSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.