Article

Deep learning-based decoding of axonal ultrastructure in gene-edited mice using electron microscopy imaging

2026-05-27

Abstract excerpt

Myelin forms an insulating sheath around axons enabling both rapid and energy-efficient conduction of action potentials and myelin abnormalities or loss can lead to severe motor, sensory, and cognitive impairment. While electron microscopy can resolve multiple axonal components that are affected myelin, their large-scale quantitative analysis is both difficult and time consuming. To overcome such limitations, we d...

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Literature Corpus work: a08a5e43-e3af-56f6-82a0-55eddd4adf5d
DOI: 10.64898/2026.05.26.727755

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