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Article

Carbamoyl phosphate synthetase polymorphisms as a risk factor for necrotizing enterocolitis.

Pediatric research - 1 Aug 2007

Moonen Rob M J, Paulussen Aimee D C, Souren Nicole Y P, Kessels Alfons G H, Rubio-Gozalbo M Estela, Villamor Eduardo

Abstract excerpt

A C-to-A nucleotide transversion (T1405N) in the gene that encodes carbamoyl-phosphate synthetase 1 (CPS1) has been correlated with low plasma concentrations of L-arginine in neonates. As plasma L-arginine concentrations are decreased in premature infants with necrotizing enterocolitis (NEC), we hypothesized that the CPS1 T1405N polymorphism would correlate with the presence of NEC. We analyzed the CPS1 genotypes...

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Source

Identifiers

PMID: 17597649
DOI: 10.1203/PDR.0b013e3180a0324e

Genes

CPS1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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