Article
IS -94INS/DELATTG POLYMORPHISM IN THE NUCLEAR FACTOR KAPPA-B1 GENE (NFKB1) ASSOCIATED WITH NECROTIZING ENTEROCOLITIS?
Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery - 1 Jan 2023
Ferdinando Danielle Lopes Teixeira, Fraga Fernanda Del Campo Braojos, Piatto Vânia Belintani, Souza Antônio Soares
Abstract excerpt
BACKGROUND: Abnormalities in the different stages of the intestinal maturation process cause metabolic and molecular changes. Among the genetic alterations associated with necrotizing enterocolitis, the -94ins/delATTG polymorphism in NFKB1 gene leads to unregulated activation of the NFKB protein due to an increase in the inherent pro-inflammatory state of the premature intestine. AIMS: To determine the prevalence...
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