Article
Long-term persistence of transmitted HIV drug resistance in male genital tract secretions: implications for secondary transmission.
The Journal of infectious diseases - 1 Aug 2007
Smith Davey M, Wong Joseph K, Shao Hai, Hightower George K, Mai Stephanie H T, Moreno Joseph M, Ignacio Caroline C, Frost Simon D W, Richman Douglas D, Little Susan J
Abstract excerpt
BACKGROUND: Transmitted drug-resistant HIV slowly reverts in the blood to drug-sensitive virus. The environment of the male genital tract (MGT) may result in even slower rates of reversion to drug susceptibility. METHODS: We measured the decay of resistance in longitudinally collected blood and semen samples from 5 individuals newly infected with HIV containing resistance mutations to nonnucleoside...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
