Article
A case report of a patient carrying CYP2C9*3/4 genotype with extremely low warfarin dose requirement.
Journal of Korean medical science - 1 Jun 2007
Lee Soo Youn, Nam Myung Hyun, Kim June Soo, Kim Jong Won
Abstract excerpt
We report a case of intolerance to warfarin dosing due to impaired drug metabolism in a patient with CYP2C9*3/*4. A 73-yr-old woman with atrial fibrilation was taking warfarin. She attained a high prothrombin time international normalized ratio (INR) at the standard doses during the induction of anticoagulation and extremely low dose of warfarin (6.5 mg/week) was finally chosen to reach the target INR. Genotyping...
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