Article
Polymorphism of XRCC1 predicts overall survival of gastric cancer patients receiving oxaliplatin-based chemotherapy in Chinese population.
European journal of human genetics : EJHG - 1 Oct 2007
Liu Baorui, Wei Jia, Zou Zhengyun, Qian Xiaoping, Nakamura Takahiro, Zhang Wei, Ding Yitao, Feng Jifeng, Yu Lixia
Abstract excerpt
Pharmacogenetic advances in cancer chemotherapy have the potential to predict clinical benefit to particular regimens. Platinum agents have shown to be effective in the treatment of gastric cancer. We assessed whether single nucleotide polymorphisms (SNPs) in xeroderma pigmentosum group D (XPD), X-ray repair cross complementing group 1 (XRCC1) and glutathione S-transferase P1 (GSTP1) predicted overall survival in...
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