Article
Association between polymorphisms in XRCC1 gene and treatment outcomes of patients with advanced gastric cancer: a systematic review and meta-analysis.
PloS one - 1 Jan 2014
Cao Zhuo, Song Jia, Wang Jun, Guo Xufeng, Yu Shijie, Dong Weiguo
Abstract excerpt
BACKGROUND: Many reports have shown inconsistent results on the relationship between single nucleotide polymorphisms (SNPs) of X-ray repair cross complementing protein (XRCC1) gene and platinum-based chemotherapeutic efficacy. This meta-analysis aimed to summarize published data about the association between two SNPs of XRCC1 (Arg194Trp and Arg399Gln) and treatment outcomes of patients with advanced gastric...
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