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Article

Immune analysis on mtHSV mediated tumor therapy in HSV-1 seropositive mice.

Cancer biology & therapy - 1 May 2007

Zhu Huabin, Su Yue, Zhou Shumin, Xiao Wei, Ling Weifang, Hu Baoli, Liu Yingle, Qi Yipeng

Abstract excerpt

We previously reported that the mutant virus of HSV (mtHSV) mediated tumor therapy was efficacious in Balb/c and nude mice. However, it is significant to know whether mtHSV works in HSV-1 tumor seropositive individuals because many patients with HSV-1 seropositivity have been found in clinical trial. Here we asked whether the oncolytic effect of mtHSV is influenced under condition of HSV-1 seropositivity. In this...

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Identifiers

PMID: 17592250
DOI: 10.4161/cbt.6.5.3953

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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