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Article

Insights into the complex regulation of rpoS in Borrelia burgdorferi.

Molecular microbiology - 1 Jul 2007

Burtnick Mary N, Downey Jennifer S, Brett Paul J, Boylan Julie A, Frye Jonathan G, Hoover Timothy R, Gherardini Frank C

Abstract excerpt

Co-ordinated regulation of gene expression is required for the transmission and survival of Borrelia burgdorferi in different hosts. The sigma factor RpoS (sigma(S)), as regulated by RpoN (sigma(54)), has been shown to regulate key virulence factors (e.g. OspC) required for these processes. As important, multiple signals (e.g. temperature, pH, cell density, oxygen) have been shown to increase the expression of...

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Source

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Identifiers

PMID: 17590233
DOI: 10.1111/j.1365-2958.2007.05813.x
PMCID: PMC1976401

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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