Article
Endostatin gene variation and protein levels in breast cancer susceptibility and severity.
BMC cancer - 22 Jun 2007
Balasubramanian Sabapathy P, Cross Simon S, Globe Jenny, Cox Angela, Brown Nicola J, Reed Malcolm W
Abstract excerpt
BACKGROUND: Endostatin is a potent endogenous anti-angiogenic agent which inhibits tumour growth. A non-synonymous coding polymorphism in the Endostatin gene is thought to affect Endostatin activity. We aimed to determine the role of this Endostatin polymorphism in breast cancer pathogenesis and...
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