Article
Drosophila dopamine synthesis pathway genes regulate tracheal morphogenesis.
Developmental biology - 1 Aug 2007
Hsouna Anita, Lawal Hakeem O, Izevbaye Iyare, Hsu Tien, O'Donnell Janis M
Abstract excerpt
While studying the developmental functions of the Drosophila dopamine synthesis pathway genes, we noted interesting and unexpected mutant phenotypes in the developing trachea, a tubule network that has been studied as a model for branching morphogenesis. Specifically, Punch (Pu) and pale (ple) mutants with reduced dopamine synthesis show ectopic/aberrant migration, while Catecholamines up (Catsup) mutants that...
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