Article
A UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase is required for epithelial tube formation.
The Journal of biological chemistry - 5 Jan 2007
Tian E, Ten Hagen Kelly G
Abstract excerpt
Epithelial tubes are essential for the proper function of a diverse array of eukaryotic organs. Here we present a novel class of genes required for maintaining epithelial cell shape, polarity, and paracellular barrier function in the Drosophila embryonic tracheal system. Mutations in one member of the UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase family (pgant35A) are recessive lethal and result in...
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