Article
Mutation spectrum in FE1-MUTA(TM) Mouse lung epithelial cells exposed to nanoparticulate carbon black.
Environmental and molecular mutagenesis - 1 May 2011
Jacobsen Nicklas Raun, White Paul A, Gingerich John, Møller Peter, Saber Anne Thoustrup, Douglas George R, Vogel Ulla, Wallin Håkan
Abstract excerpt
It has been shown previously that carbon black (CB), Printex 90 exposure induces cII and lacZ mutants in the FE1-Muta(TM) Mouse lung epithelial cell line and causes oxidatively damaged DNA and the production of reactive oxygen species (ROS). The purpose of this study was to determine the mutation spectrum in the cII gene of Printex 90 exposed cells. Cells exposed to CB have a substantially different mutation...
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