Article
Genetic polymorphisms of ataxia telangiectasia mutated affect lung cancer risk.
Human molecular genetics - 1 Apr 2006
Kim Jin Hee, Kim Heon, Lee Kye Young, Choe Kang-Hyeon, Ryu Jeong-Seon, Yoon Ho Il, Sung Sook Whan, Yoo Keun-Young, Hong Yun-Chul
Abstract excerpt
The ataxia telangiectasia mutated (ATM) gene is known to be activated by DNA damage and involved in cell cycle arrest, apoptosis and DNA repair. Therefore, ATM gene polymorphisms may act as important factors predicting individual susceptibility to lung cancer. To evaluate the role of ATM gene pol...
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