Article
Responses of <i>Pseudomonas aeruginosa</i> to low oxygen indicate that growth in the cystic fibrosis lung is by aerobic respiration
16 Jun 2007
Abstract excerpt
Pseudomonas aeruginosa in the lungs of cystic fibrosis patients grows to high densities in mucopurulent material that is depleted in oxygen. Some have concluded that growth in these circumstances is dependent on anaerobic nitrate respiration. Here we present data in favour of the alternative hypothesis that microaerobic respiration is the predominant mode of P. aeruginosa growth in the cystic fibrosis lung. We...
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